Robust THP Transceiver Designs for Multiuser MIMO Downlink with Imperfect CSIT

In this paper, we present robust joint non-linear transceiver designs for multiuser multiple-input multiple-output (MIMO) downlink in the presence of imperfections in the channel state information at the transmitter (CSIT). The base station (BS) is equipped with multiple transmit antennas, and each user terminal is equipped with one or more receive antennas. The BS employs Tomlinson-Harashima precoding (THP) for inter-user interference pre-cancellation at the transmitter. We consider robust transceiver designs that jointly optimize the transmit THP filters and receive filter for two models of CSIT errors. The first model is a stochastic error (SE) model, where the CSIT error is Gaussian-distributed. This model is applicable when the CSIT error is dominated by channel estimation error. In this case, the proposed robust transceiver design seeks to minimize a stochastic function of the sum mean square error (SMSE) under a constraint on the total BS transmit power. We propose an iterative algorithm to solve this problem. The other model we consider is a norm-bounded error (NBE) model, where the CSIT error can be specified by an uncertainty set. This model is applicable when the CSIT error is dominated by quantization errors. In this case, we consider a worst-case design. For this model, we consider robust i) minimum SMSE, ii) MSE-constrained, and iii) MSE-balancing transceiver designs. We propose iterative algorithms to solve these problems, wherein each iteration involves a pair of semi-definite programs (SDP). Further, we consider an extension of the proposed algorithm to the case with per-antenna power constraints.Comment: Accepted for publication in EURASIP Journal on Advances in Signal Processing: Special Issue on Multiuser MIMO Transmission with Limited Feedback, Cooperation, and Coordinatio

Relay Selection and Transceiver Design for Joint Wireless Information and Energy Transfer in Cooperative Networks

In this paper, we consider optimal transceiver design and relay selection for simultaneous transfer of data and energy in a cooperative network consisting of amplify-and-forward (AF) relays. In this context, we address two different problems and propose optimal relay selection and transceiver processing. Furthermore, the problems are formulated for both time switching (TS) and power splitting (PS) schemes. The first problem is the maximization of overall rate while ensuring a minimum harvested energy at the receiver. For this problem, we perform computations of optimal fractions to distribute the received signal corresponding to TS and PS schemes, the relay weighing coefficients, and optimal relay selection. In the second problem, optimal resource allocation for maximizing the overall harvested energy at the user under constraints on the minimum achievable rate has been formulated. For this problem, we propose a suitable solution to meet the requirements for both TS and PS. For both the problems, we obtain a closed form solution. Finally, the performance of proposed design under various operating conditions and parameter values are illustrated with a comparison between TS and PS schemes

Čvrsta disperzija meloksikama: faktorijalno dizajnirani dozirani pripravak za gerijatrijsku populaciju

The objective of the present work was to improve the dissolution properties of the poorly water-soluble drug meloxicam by preparing solid dispersions with hydroxyethylcellulose (HEC), mannitol and polyethylene glycol (PEG) 4000 and to develop a dosage form for geriatric population. Differential scanning calorimetry, X–ray diffractometry, Fourier transform infrared spectroscopy and scanning electron microscopy were used to investigate the solid-state physical structure of the prepared solid dispersions. Higher in vitro dissolution of solid dispersions was recorded compared to their corresponding physical mixtures and the pure drug. PEG 4000 in 1:9 drug to carrier ratio exhibited the highest drug release (100.2%), followed by mannitol (98.2%) and HEC (89.5%) in the same ratio. Meloxicam-PEG 4000 solid dispersion was formulated into suspension and optimization was carried out by 23 factorial design. Formulations containing higher levels of methyl cellulose and higher levels of either sodium citrate or Tween 80 exhibited the highest drug release.Cilj rada bio je poboljšati topljivost meloksikama u vodi pripravom čvrstih disperzija s hidroksietilcelulozom (HEC), manitolom i polietilen glikolom 4000 (PEG 4000) te razviti dozirani pripravaka za gerijatrijsku populaciju. Za ispitivanje fizičke strukture pripravljenih čvrstih disperzija korištene su diferencijalna pretražna kalorimetrija, difraktometrija rentgentskim zrakama, FTIR i pretražna elektronska mikroskopija. Čvrste disperzije su u in vitro uvjetima pokazale bolju topljivost u odnosu na fizičku smjesu i čistu ljekovitu tvar. Najbolje oslobađanje lijeka (100,2%). postignuto je iz disperzija s PEG 4000 (omjer ljekovite tvari i nosača 1:9). Slijede manitol (98,2%) i HEC (89,5%) (isti omjer meloksikama i polimera). Čvrsta disperzija meloksikama s PEG 4000 prevedena je u suspenziju te optimirana 23 faktorijalnim dizajnom. Najbolje oslobađanje ljekovite tvari postignuto je iz pripravaka koji sadrže veći udio etilceluloze i natrijevog citrata, odnosno Tween 80